Retinocoroidopatía in perdigonada - Wikipedia, the free encyclopedia

Retinocoroidopatía in perdigonada - Wikipedia, the free encyclopedia

Retinocoroidopatía in perdigonada - Wikipedia, the free encyclopedia

Characteristics of hypopigmentation in Retinocoroidopathy in Pest Control

Retinocorophoidopathy in Pest Control is also known as Chorioretinopathy in pelvic or simply pelvic retinopathy is a rare bilateral posterior form of uveitis affecting the human eye. Severe and progressive inflammation of the choroid and retina.

The affected individuals are almost exclusively Caucasian and usually diagnosed from the fourth to the sixth decade of their lives.

Pathophysiology < / h2>

Retinocoroidopathy in parched is a rare form of posterior uveitis and is considered 1-3% of cases of uveitis in general. Retinocoroidopathy in parachute is thought to be an autoimmune disease. The disease has a strong association with the human leukocyte antigen (HLA) -A29, which is the strongest association between disease and the documented class (85 to 97.5% of patients are HLA-A29 positive). This suggests a role for T-lymphocytes in pathogenesis. Retinocoroidopathy in pinworms is associated with Interleukin 17 | IL-17, a cytokine contrast of TH17 cells that play an important role in autoimmunity.

The disease typically affects middle or advanced age Caucasian. HLA-A29 is less prevalent in Asia and no cases of retinochoroidopathy have been reported in this continent. When spotted retinochoroidopathy is suspected, the person is usually tested for HLA-A29 positive. However, HLA-A29 tests are not considered necessary for a definitive diagnosis because HLA-A29 is also common in the general healthy population (7%). In addition (genetic or environmental) or unknown factors could be associated with HLA-A29 in pathogenesis.

The name of the disease is given by the small colored spots on the retina, scattered in a pattern such as those shot from birds, but those points may not be present in the early stages.


Retinocoroidopathy in shotguns may show resistance to treatment. With immunosuppressive therapy with oral corticosteroids could somehow be effective in slowing the inflammatory process associated with the disease, preserving the visual integrity as much as possible. Long-term use of such medications should be closely monitored, however, due to discomfort, potential impairment and life threatening side effects, subsequent patients with retinocoroidopathy in pelvic treated with systemic corticosteroid immunomodulatory therapy were treated with systemic immunosuppressants.

Immunosuppressive drugs such as monoclonal antibodies, daclizumab, cyclosporine, and methotrexate have been tried as effective treatment options for retinochoroidopathy in pelvic. Substantial reduction and even stabilization of vitreous inflammation and retinal vasculitis have been demonstrated by electoretinography during daclizumab therapy (IL-2 receptor blocker). This is also supported by observation of elevated levels of IL-2 in the eyes of patients.

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